The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2021

Filed:

Jul. 17, 2019
Applicant:

Biopharmx, Inc., San Jose, CA (US);

Inventors:

Xin Chen, Palo Alto, CA (US);

Maiko C. Hermsmeier, San Jose, CA (US);

Diana Lac, San Francisco, CA (US);

Douglas W. Thomas, Palo Alto, CA (US);

Noymi Yam, Sunnyvale, CA (US);

Akira Yamamoto, Cupertino, CA (US);

Assignee:

BioPharmX, Inc., Campbell, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/65 (2006.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 9/00 (2006.01); A61P 17/10 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/65 (2013.01); A61K 9/0014 (2013.01); A61K 9/08 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61P 17/10 (2018.01); A61P 31/04 (2018.01); Y02A 50/30 (2018.01);
Abstract

Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises minocycline, a magnesium salt, and a sulfite compound in a non-aqueous solvent. In yet another aspect, the topical composition comprises a tetracycline-class drug, a source of magnesium, a monohydric aliphatic alcohol, and a polyol, wherein (i) the ratio between the monohydric aliphatic alcohol and the propylene glycol is in the range of 1:1 to 99:1 by weight and (ii) the tetracycline-class drug is dissolved in the topical composition.


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