The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2021
Filed:
Aug. 19, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Andrei Faraon, La Canada Flintridge, CA (US);
Amir Arbabi, Pasadena, CA (US);
Yu Horie, Pasadena, CA (US);
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/145 (2006.01); G01N 21/65 (2006.01); G01J 3/44 (2006.01); G02B 27/10 (2006.01); G01J 3/18 (2006.01); G01J 3/12 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1455 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); G01J 3/12 (2013.01); G01J 3/18 (2013.01); G01J 3/44 (2013.01); G01N 21/65 (2013.01); G02B 27/1006 (2013.01); G02B 27/1086 (2013.01); A61B 2560/0431 (2013.01); A61B 2562/0238 (2013.01); A61B 2562/0285 (2013.01); G01J 2003/1213 (2013.01); G01N 2201/068 (2013.01);
Abstract
A solution containing a target molecule and a reference molecule is illuminated to obtain Raman signals. An optical metasurface is used as a diffractive optical element to split the Raman signal from the target molecule and the Raman signal from the reference molecule. The target and reference Raman signals can be detected at different locations with different photodetectors, and the target molecule concentration in the solution is determined by comparing the target and reference Raman signals.