The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Jun. 26, 2015
Selventa, Inc., Cambridge, MA (US);
Philip Morris Products, S.a., Neuchatel, CH;
Ty Matthew Thomson, Arlington, MA (US);
Dmitry Vasilyev, Somerville, MA (US);
Florian Martin, Peseux, CH;
Other;
Abstract
Disclosed herein are system, method, and computer program product embodiments for determining a score for a degree of activation of a biological network. An embodiment constructs a tree graph comprising a root node and a set of child nodes. The root node represents a biological network having a reference node and causal connections among a set of nodes that represent biological entities, biological processes, or other biological networks. Each child node represents a particular node in the biological network and is connected to the root node by a signed, directed edge pointing from the root node to that child node. Each child node also has an associated weight based on one or more paths connecting the child node to the reference node in the biological network. The embodiment further scores the tree graph based on scores assigned to the child nodes and the signs of the singed, directed edges.