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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10877021 B1

PDFFull Text
Date of Patent:
Dec. 29, 2020

Filed:

Apr. 21, 2017

Device for biological material detection, detection apparatus for biological material detection, method for measuring ion current, and method for identifying biological material

Applicants:

Osaka University, Osaka, JP;

Tokyo Institute of Technology, Tokyo, JP;

National University Corporation Tokyo Medical and Dental University, Tokyo, JP;

Inventors:

Makusu Tsutsui, Osaka, JP;

Kazumichi Yokota, Osaka, JP;

Masateru Taniguchi, Osaka, JP;

Tomoji Kawai, Osaka, JP;

Mina Okochi, Tokyo, JP;

Masayoshi Tanaka, Tokyo, JP;

Yoshinobu Baba, Aichi, JP;

Noritada Kaji, Aichi, JP;

Takao Yasui, Aichi, JP;

Yuji Miyahara, Tokyo, JP;

Yukichi Horiguchi, Tokyo, JP;

Assignees:

OSAKA UNIVERSITY, Osaka, JP;

TOKYO INSTITUTE OF TECHNOLOGY, Tokyo, JP;

NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, Tokyo, JP;

Attorney:

McDermott Will & Emery LLP

Primary Examiner:

Melanie Brown

Int. Cl.
CPC ...
G01N 33/487 (2006.01); C12Q 1/04 (2006.01); C12M 1/34 (2006.01); C12Q 1/6825 (2018.01); C07K 17/14 (2006.01); G01N 15/12 (2006.01); C07K 17/08 (2006.01); G01N 33/483 (2006.01); C12M 1/00 (2006.01); C12Q 1/68 (2018.01); C12M 1/26 (2006.01); G01N 33/566 (2006.01); G01N 33/569 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C07K 17/08 (2013.01); C07K 17/14 (2013.01); C12M 1/00 (2013.01); C12M 1/34 (2013.01); C12M 33/00 (2013.01); C12Q 1/04 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6825 (2013.01); G01N 15/1218 (2013.01); G01N 33/483 (2013.01); G01N 33/566 (2013.01); G01N 33/56983 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01);
Abstract

A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.

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