The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Dec. 17, 2015
Applicants:
Aravive Biologics, Inc., Houston, TX (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Raymond Tabibiazar, Portola Valley, CA (US);
Amato J. Giaccia, Stanford, CA (US);
Mihalis Kariolis, Stanford, CA (US);
Yu Rebecca Miao, San Jose, CA (US);
Assignees:
Aravive Biologics, Inc., Houston, TX (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/45 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C12Y 207/10001 (2013.01); A61K 38/17 (2013.01); A61K 38/45 (2013.01); A61K 39/395 (2013.01);
Abstract
Compositions and methods are provided for treating fibrosis in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits AXL, MER or Tyro3 protein activity, for example by inhibition of the binding interaction between AXL, MER or Tyro3 and its ligand GAS6.