The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Feb. 28, 2007
Jochen Huehn, Berlin, DE;
Stefan Floess, Berlin, DE;
Alf Hamann, Eichwalde, DE;
Sven Olek, Berlin, DE;
Udo Baron, Berlin, DE;
Jochen Huehn, Berlin, DE;
Stefan Floess, Berlin, DE;
Alf Hamann, Eichwalde, DE;
Sven Olek, Berlin, DE;
Udo Baron, Berlin, DE;
Epiontis GmbH, Berlin, DE;
Charite-Universitatsmedizin Berlin, Berlin, DE;
Abstract
The present invention relates to a method, in particular an in vitro method for identifying FoxP3-positive regulatory T cells, preferably CD25CD4regulatory T cells of a mammal, comprising analysing the methylation status of at least one CpG position in the gene foxp3 or an orthologous or paralogous gene thereof, and the use of DNA-methylation analysis of the gene of the transcription factor FoxP3 for a detection and quality assurance and control of regulatory T cells. Furthermore, the present invention relates to a kit for performing the above methods as well as respective uses.