The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Mar. 10, 2015
Applicants:

Bayer Cropscience Lp, Research Triangle Park, NC (US);

Bayer Cropscience Ag, Monheim, DE;

Inventors:

Manuel Dubald, Raleigh, NC (US);

Roxanne Armstrong, Cary, NC (US);

Fabien Poree, Frankfurt, DE;

Cheryl Peters, Raleigh, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8274 (2013.01); C12N 9/0069 (2013.01); C12Y 113/11027 (2013.01);
Abstract

In the present invention, HPPD enzymes and plants containing them showing a full tolerance against several classes of HPPD-inhibitors are described. A set of HPPD enzymes have been designed which have either no or only a significantly reduced affinity to HPPD inhibitors and, at the same time, the rate of dissociation of the HPPD inhibitors of the enzyme is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.


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