The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Jun. 29, 2018
Applicants:
Biomarin Technologies B.v., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Inventor:
Judith Christina Theodora Van Deutekom, Dordrecht, NL;
Assignees:
BioMarin Technologies B.V., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 31/56 (2006.01); A61K 31/57 (2006.01); A61K 38/17 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01); A61K 31/573 (2006.01); A61K 31/58 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/56 (2013.01); A61K 31/57 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61K 31/7088 (2013.01); A61K 38/1719 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/31 (2013.01); C12N 2310/313 (2013.01); C12N 2310/314 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/346 (2013.01); C12N 2320/31 (2013.01); C12N 2320/33 (2013.01);
Abstract
The invention relates a method wherein a molecule is used for inducing and/or promoting skipping of at least one of exon 43, exon 46, exons 50-53 of the DMD pre-mRNA in a patient, preferably in an isolated cell of a patient, the method comprising providing the cell and/or the patient with a molecule. The invention also relates to the molecule as such.