The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Nov. 25, 2013
Corning Incorporated, Corning, NY (US);
Ronald Allen Faris, Elmira, NY (US);
Yulong Hong, Painted Post, NY (US);
Joydeep Lahiri, Painted Post, NY (US);
Jin Liu, Painted Post, NY (US);
Olivia Grace Weeks, Brookline, MA (US);
Ronald Allen Faris, Elmira, NY (US);
Yulong Hong, Painted Post, NY (US);
Joydeep Lahiri, Painted Post, NY (US);
Jin Liu, Painted Post, NY (US);
Olivia Grace Weeks, Brookline, MA (US);
Corning Incorporated, Corning, NY (US);
Abstract
Cell culture compositions containing LFM-A13 or a structurally related compound can enhance global hepatic function. For example, LFM-A13 is shown to enhance levels of a broad variety of drug metabolism enzymes, including CYP enzymes, and other hepatic enzymes. LFM-A13 is also shown to promote differentiation of stem cells into hepatocytes. LFM-A13 and structurally related compounds can be used in cell culture to enhance global drug metabolism of liver cells for enhanced in vitro study the effects of drug metabolism on other candidate drug compounds.