The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Jan. 07, 2019
Applicants:

Baxalta Incorporated, Bannockburn, IL (US);

Baxalta Gmbh, Glattpark, CH;

Inventors:

Wolfgang Teschner, Vienna, AT;

Hans-Peter Schwarz, Vienna, AT;

Ruth Madlener, Vienna, AT;

Sonja Svatos, Berg, AT;

Azra Pljevljakovic, Vienna, AT;

Alfred Weber, Vienna, AT;

Assignees:

Baxalta Incorporated, Bannockburn, IL (US);

Baxalta GmbH, Glattpark, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/06 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 38/17 (2006.01); A61K 47/18 (2017.01); C07K 1/30 (2006.01); C07K 1/36 (2006.01); A61K 35/16 (2015.01); B01D 15/12 (2006.01); B01D 15/36 (2006.01); B01D 15/42 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/065 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 35/16 (2013.01); A61K 38/1709 (2013.01); A61K 39/39525 (2013.01); A61K 47/183 (2013.01); B01D 15/12 (2013.01); B01D 15/362 (2013.01); B01D 15/363 (2013.01); B01D 15/424 (2013.01); C07K 1/30 (2013.01); C07K 1/36 (2013.01);
Abstract

The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and\or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content.


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