The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Nov. 13, 2019
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Jean Anne Chmielewski, Lafayette, IN (US);
Mohamed Seleem, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 9/00 (2006.01); A61P 31/04 (2006.01); A61K 47/55 (2017.01); A61K 31/7036 (2006.01); A61K 49/00 (2006.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 9/008 (2013.01); A61K 31/7036 (2013.01); A61K 47/552 (2017.08); A61K 49/0056 (2013.01); A61P 31/04 (2018.01); A61K 38/00 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure relates to novel antibacterial cell-penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives. The novel antibacterial cell-penetrating peptides of the present invention with shorter linker between a pyrrolidine ring and a guanidine group provide unexpectedly higher potency against a broader scope of bacterial.