The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Jun. 20, 2018
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Regents of the University of Minnesota, Minneapolis, MN (US);
James L. Riley, Downingtown, PA (US);
Carl H. June, Merion Station, PA (US);
Bruce R. Blazar, Golden Valley, MN (US);
Keli Hippen, Robbinsdale, MN (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Regents of the University of Minnesota, Minneapolis, MN (US);
Abstract
The present invention provides methods and compositions for converting non-Tregs into Tregs. The converted Tregs are referred to as inducible Tregs (iTregs). The iTregs are useful for preventing, suppressing, blocking or inhibiting an immune response. For example the iTregs are useful for preventing rejection of a transplanted tissue in a human or other animal host, or protecting against graft vs host disease. The iTregs can also be used to treat autoimmune diseases.