The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Dec. 04, 2014
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Erika Darrah, Baltimore, MD (US);

Ami A. Shah, Ellicot City, MD (US);

Livia A. Casciola-Rosen, Pikesville, MD (US);

Antony Rosen, Pikesville, MD (US);

Christine Joseph, Baltimore, MD (US);

Bert Vogelstein, Baltimore, MD (US);

Kenneth W. Kinzler, Baltimore, MD (US);

Nickolas Papadopoulos, Towson, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0008 (2013.01); A61K 38/00 (2013.01); A61K 2039/585 (2013.01);
Abstract

Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers.


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