The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Sep. 07, 2018
Applicant:

Wayne State University, Detroit, MI (US);

Inventor:

Aloke K. Dutta, Troy, MI (US);

Assignee:

WAYNE STATE UNIVERSITY, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/496 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); A61K 31/496 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01);
Abstract

A compound having formula IA is useful for treating a neurodegenerative disease: or a pharmaceutically acceptable salt or ester thereof, where R, R, R, R, Rare delineated substituents; Ais a Caryl group, Cheteroaryl group, substituted 3-hydroxypyridin-4(1H)-one, with i hydrogen atoms replaced with Rand j hydrogen atoms replaced with R; p is an integer from 1 to 6; X, Yare each independently CH or N; M is absent or a divalent linking moiety in which Z is repeated m times; m is an integer from 0 to 5; i, j are each independently 0, 1, 2, or 3; and o is 0, 1, 2, 3, or 4.


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