The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Jan. 20, 2017
Applicant:

Tasly Pharmaceutical Group Co., Ltd., Tianjin, CN;

Inventors:

Min Han, Tianjin, CN;

Xiaohui Ma, Tianjin, CN;

Wangyi Zhou, Tianjin, CN;

Yanyong Liu, Tianjin, CN;

Yanchuan Li, Tianjin, CN;

Jing Wang, Tianjin, CN;

Shuiping Zhou, Tianjin, CN;

He Sun, Tianjin, CN;

Yonghong Zhu, Tianjin, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/36 (2006.01); A61K 31/357 (2006.01); A61K 31/4525 (2006.01); A61K 31/166 (2006.01); A61P 25/22 (2006.01); A61K 31/496 (2006.01); C07D 317/60 (2006.01); C07C 235/34 (2006.01); C07D 295/192 (2006.01);
U.S. Cl.
CPC ...
A61K 31/357 (2013.01); A61K 31/166 (2013.01); A61K 31/4525 (2013.01); A61K 31/496 (2013.01); A61P 25/22 (2018.01); C07C 235/34 (2013.01); C07D 295/192 (2013.01); C07D 317/60 (2013.01);
Abstract

Disclosed is an application of substituted cinnamamide derivatives in the preparation of anti-anxiety medications, the substituted cinnammide derivatives are compounds having the structure of formula (I) or pharmaceutically acceptable salts thereof, wherein, Ris —H, —OH, —F, —Cl, —Br, —I, —OCH, —OCF, —OCHF, —OCHF, —CF, —CHF, —CHF, —CH, —CHCH, —CFCH, —CN, —NO, —NHor —COOR; Ris H, C-Clinear alkyl, C-Cbranched alkyl, C-Ccyclic alkyl, C-Chydroxyalkyl or a N-substituted piperazine-derived group; or Ris a group forming with adjacent Y a tetrahydropyrrolyl group, a piperidyl group or a cyclohexanimido group.


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