The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Jun. 23, 2016
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Burcu Aslan, Houston, TX (US);
Gabriel Lopez-Berestein, Bellaire, TX (US);
Anil K. Sood, Pearland, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/0024 (2013.01); A61K 9/5146 (2013.01); A61K 9/5161 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); A61K 9/5031 (2013.01); A61K 2300/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract
Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed.