The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Aug. 10, 2017
Applicant:
Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Inventors:
Michael L. Heien, Tucson, AZ (US);
Nicholas D. Laude, Tucson, AZ (US);
Catherine L. Kramer, Tucson, AZ (US);
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, Tucson, AZ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 10/00 (2006.01); A61K 38/08 (2019.01); A61M 1/16 (2006.01); G01N 30/72 (2006.01); B01D 61/24 (2006.01); B01D 61/30 (2006.01); G01N 30/02 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14528 (2013.01); A61B 5/0002 (2013.01); A61B 10/0045 (2013.01); A61K 38/08 (2013.01); A61M 1/1603 (2014.02); B01D 61/246 (2013.01); B01D 61/30 (2013.01); G01N 30/02 (2013.01); G01N 30/7206 (2013.01); G01N 2030/027 (2013.01); G01N 2030/8822 (2013.01);
Abstract
Methods and systems for quantifying blood brain barrier (BBB) permeation of glycosylated peptides. The methods and systems feature microdialysis probes and mechanisms for infusing preservative agents into the outflow tubes of the microdialysis probes. The preservative agents help reduce unwanted degradation of the glycosylated peptides or other compounds, which can lead to a more accurate and complete analysis of the outflow tube perfusate.