The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Apr. 09, 2015
Corning Incorporated, Corning, NY (US);
David Alan Kenney, Greenville, NH (US);
Nikolaos Pantelis Kladias, Horseheads, NY (US);
Shang-Pin Kwei, Boston, MA (US);
Aravind Raghavan Rammohan, Big Flats, NY (US);
Joseph Christopher Wall, Southborogh, MA (US);
Kathy Marie Youngbear, Cambridge, MA (US);
Corning Incorporated, Corning, NY (US);
Abstract
A 5-liter bioreactor vessel enables a substantial increase in the volume of biological media that can be cultivated in the vessel compared to conventional designs. Moreover, when agitated at 1.5× the shaking frequency of a conventional 3-liter bioreactor (i.e., 90 rpm versus 60 rpm), the 5-liter vessel achieves a 19% increase in cell aeration without exceeding the maximum shear stress limit for cell viability. The 5-liter vessel optionally includes a plurality of internal baffles configured to disrupt the liquid vortex and reduce the maximum shear stress transferred to biomedia contained within the vessel.