The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Jul. 22, 2017
Applicant:
New York University, New York, NY (US);
Inventors:
Thomas M. Wisniewski, Staten Island, NY (US);
Fernando Goni, New York, NY (US);
Assignee:
NEW YORK UNIVERSITY, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61P 25/28 (2006.01); C07K 7/06 (2006.01); C07K 16/18 (2006.01); C07K 14/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61P 25/28 (2018.01); C07K 7/06 (2013.01); C07K 14/00 (2013.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01);
Abstract
The present invention relates to antibodies and binding fragments thereof that bind the β-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding to the non-toxic, non-pathological forms of these proteins or peptides These antibodies and binding fragments thereof are suitable for the diagnosis, prevention, and treatment of protein conformational disorders including all amyloid diseases.