The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2020

Filed:

Mar. 31, 2017
Applicants:

Omeros Corporation, Seattle, WA (US);

University of Leicester, Leicester, GB;

Inventors:

Gregory A. Demopulos, Mercer Island, WA (US);

Hans-Wilhelm Schwaeble, Mountsorrel, GB;

Thomas Dudler, Bellevue, WA (US);

Larry Tjoelker, Kirkland, WA (US);

Assignee:

University of Leicester, Leicester, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 39/00 (2006.01); A61P 35/04 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61P 27/02 (2018.01); A61P 35/04 (2018.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/54 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

In one aspect, the present invention provides methods for preventing, treating, reverting and/or delaying angiogenesis in a mammalian subject suffering from, or at risk for developing, an angiogenesis-dependent disease or condition, comprising administering to the subject an amount of a MASP-2 inhibitory agent effective to inhibit angiogenesis. In some embodiments of these aspects of the invention, the MASP-2 inhibitory agent is a MASP-2 antibody or fragment thereof.


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