The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2020

Filed:

Jan. 28, 2016
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Guang-Liang Jiang, Irvine, CA (US);

Catherine C. Turkel, Newport Coast, CA (US);

Michael E. Stern, Mission Viejo, CA (US);

Christopher S. Schaumberg, Huntington Beach, CA (US);

Wendy M. Blanda, Tustin, CA (US);

Assignee:

ALLERGAN, INC., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 31/04 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01);
U.S. Cl.
CPC ...
A61L 31/042 (2013.01); A61L 31/145 (2013.01); A61L 31/16 (2013.01); A61L 2300/402 (2013.01); A61L 2300/41 (2013.01); A61L 2300/426 (2013.01); A61L 2300/43 (2013.01); A61L 2300/622 (2013.01); A61L 2300/624 (2013.01); A61L 2400/06 (2013.01); A61L 2430/24 (2013.01);
Abstract

The present invention relates to formulations for administration to a joint fat pad of a subject, and to methods of treating joint pain, inflammation or disease. The disclosed formulations are intended for local administration to the joint fat pad to provide sustained release of a therapeutic agent to the joint cavity and surrounding tissues. The joint may be an arthritic joint, an injured joint or a surgically replaced joint. The therapeutic agent may be an analgesic agent, an anti-inflammatory agent or an immunosuppressive agent. A single administration of the formulation to the joint fat pad delivers a therapeutically effective amount of the therapeutic agent with reduced systemic exposure relative to a single systemic or a single intra-articular administration of a therapeutic dose of an identical therapeutic agent.


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