The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Feb. 14, 2016
Applicants:
Tsinghua University, Beijing, CN;
Beijing Protgen Ltd., Beijing, CN;
Inventors:
Assignees:
Tsinghua University, Beijing, CN;
BEIJING PROTGEN LTD., Beijing, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/17 (2006.01); C07K 14/435 (2006.01); C07K 14/78 (2006.01); A61K 47/50 (2017.01); A61P 5/50 (2006.01); A61P 35/00 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 38/1891 (2013.01); A61K 38/17 (2013.01); A61K 47/10 (2013.01); A61K 47/50 (2017.08); A61P 5/50 (2018.01); A61P 35/00 (2018.01); C07K 14/435 (2013.01); C07K 14/78 (2013.01);
Abstract
Provided is a mutant of an endostatin. The mutant has improved ATPase activity and improved activity of inhibiting angiogenesis and inhibiting tumors. Further provided is use of the mutant in treatment of angiogenesis related diseases such as tumors.