The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2020

Filed:

Dec. 15, 2016
Applicant:

Ignyta, Inc., San Diego, CA (US);

Inventors:

Gang Li, San Diego, CA (US);

Ge Wei, San Diego, CA (US);

Zachary D. Hornby, San Diego, CA (US);

Jonathan Ee-ren Lim, San Diego, CA (US);

Assignee:

IGNYTA, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/416 (2006.01); A61K 31/4439 (2006.01); A61K 31/519 (2006.01); A61K 31/37 (2006.01); A61K 31/44 (2006.01); A61K 31/365 (2006.01); A61K 31/4523 (2006.01); A61K 31/18 (2006.01); A61K 31/166 (2006.01); A61K 45/06 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); A61P 35/00 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/166 (2013.01); A61K 31/18 (2013.01); A61K 31/365 (2013.01); A61K 31/416 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/4439 (2013.01); A61K 31/4523 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.


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