The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2020

Filed:

Jul. 12, 2019
Applicant:

Liminal Biosciences Limited, Comberton, GB;

Inventors:

Lyne Gagnon, Laval, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/36 (2006.01); A61K 8/365 (2006.01); A61P 17/02 (2006.01); A61P 19/08 (2006.01); A61Q 19/08 (2006.01); C07C 57/30 (2006.01); C07C 57/32 (2006.01); C07C 57/58 (2006.01); C07C 59/52 (2006.01); C07C 59/84 (2006.01); A61K 31/192 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 8/36 (2013.01); A61K 8/365 (2013.01); A61P 17/02 (2018.01); A61P 19/08 (2018.01); A61Q 19/08 (2013.01); C07C 57/30 (2013.01); C07C 57/32 (2013.01); C07C 57/58 (2013.01); C07C 59/52 (2013.01); C07C 59/84 (2013.01);
Abstract

Described herein are compounds of Formula I, or pharmaceutically acceptable salts thereof, or combinations thereof, as well as uses thereof. Such uses include promoting tissue self-repair or tissue regeneration of an organ, stimulating the generation of tissue growth, modulating (e.g., increasing) the level of a tissue-repair marker, treating physical injury in an organ, tissue or cell, promoting wound healing, as well as anti-aging applications. Corresponding compositions, methods, kits, and uses are also described. Formula I wherein A is Calkyl, Calkyl, Calkenyl, Calkenyl, C(O)—(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F of OH; Ris H, F, OH, Calkyl, Calkyl, Calkenyl, Calkenyl, C(O)—(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F, OH, or CHPh; Ris H, F or OH; Q is 1) (CH), C(O)OH wherein m is 1 or 2 2) CH(CH)C(O)OH, 3) C(CH)C(O)OH, 4) CH(F)—C(O)OH, 5) CF—C(O)OH or 6) C(O)—C(O)OH.


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