The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2020

Filed:

Aug. 08, 2018
Applicant:

Osaka University, Osaka, JP;

Inventors:

Yoko Fukushima, Osaka, JP;

Kohji Nishida, Osaka, JP;

Toru Nakano, Osaka, JP;

Assignee:

OSAKA UNIVERSITY, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 15/00 (2006.01); G01N 33/00 (2006.01); A61K 49/00 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A61K 49/0008 (2013.01); C12N 9/12 (2013.01); C12Y 207/11001 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01);
Abstract

Provided are a non-human model animal of a retinal vascular disease that can favorably show symptoms similar to those of human retinal vascular diseases such as human diabetic retinopathy, and a method for producing the non-human model animal. In particular, provided are a non-human model animal that is suitable for establishing a method for treating, preventing, or diagnosing retinal edema, which causes highly impaired vision, and a method for producing the non-human model animal. A method for screening a drug for treating and preventing a retinal vascular disease, the method using a non-human model animal, is provided. Provided are a non-human model animal of a retinal vascular disease in which constitutively active Akt is expressed, a method for producing a non-human model animal of a retinal vascular disease in which constitutively active Akt is expressed, and a method for screening a drug for treating or preventing a retinal vascular disease.


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