The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Oct. 23, 2014
Applicant:

Mologic Limited, Thurleigh, GB;

Inventors:

Paul Davis, Sharnbrook, GB;

Gita Parekh, Milton Keynes, GB;

James Schouten, Thurleigh, GB;

Assignee:

Mologic Limited, Bedfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); G01N 33/543 (2006.01); G01N 33/558 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54386 (2013.01); C12Q 1/37 (2013.01); G01N 33/558 (2013.01); G01N 33/573 (2013.01); G01N 2333/96486 (2013.01); G01N 2800/12 (2013.01); G01N 2800/382 (2013.01);
Abstract

The present invention relates to detecting cleavage activity of an enzyme. The various aspects of the invention include an enzyme detection device, kit, method and use for detecting or measuring the presence in a test sample of the activity of an enzyme capable of cleaving a substrate. The invention also relates to indicator and binding molecules useful for carrying out the invention. The enzyme substrate contains a hidden binding site which is only revealed upon cleavage by the enzyme.


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