The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Feb. 28, 2013
Integenx Inc., Pleasanton, CA (US);
David Eberhart, Santa Clara, CA (US);
Yuan Li, Dublin, CA (US);
James Ogg, Sunnyvale, CA (US);
Ezra Van Gelder, Palo Alto, CA (US);
Stephen J. Williams, San Carlos, CA (US);
Timothy Woudenberg, San Francisco, CA (US);
Dean S. Burgi, Sunnyvale, CA (US);
William D. Nielsen, San Jose, CA (US);
IntegenX, Inc., Pleasanton, CA (US);
Abstract
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.