The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Sep. 07, 2012
Applicants:

Anthony D. Keefe, Cambridge, MA (US);

Richard W. Wagner, Cambridge, MA (US);

Alexander Litovchick, Sudbury, MA (US);

Matthew Clark, Lexington, MA (US);

John W. Cuozzo, Natick, MA (US);

Ying Zhang, Lexington, MA (US);

Paolo A. Centrella, Acton, MA (US);

Christopher D. Hupp, Shrewsbury, MA (US);

Inventors:

Anthony D. Keefe, Cambridge, MA (US);

Richard W. Wagner, Cambridge, MA (US);

Alexander Litovchick, Sudbury, MA (US);

Matthew Clark, Lexington, MA (US);

John W. Cuozzo, Natick, MA (US);

Ying Zhang, Lexington, MA (US);

Paolo A. Centrella, Acton, MA (US);

Christopher D. Hupp, Shrewsbury, MA (US);

Assignee:

X-Chem, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C40B 50/16 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C12N 15/10 (2013.01); C12N 15/1068 (2013.01); C12N 15/1093 (2013.01); C40B 50/16 (2013.01); C07B 2200/11 (2013.01);
Abstract

The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2'-substituted nucleotides, such as 2′-O-methyl or 2′-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.


Find Patent Forward Citations

Keefe, Anthony. (2020). Methods for tagging dna-encoded libraries (U.S. Patent No. 10865409). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10865409

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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