The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Nov. 10, 2017
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Sharmila Adhikari, Natick, MA (US);
Emily Frances Calderwood, Framingham, MA (US);
Dylan Bradley England, Milford, MA (US);
Alexandra E. Gould, Cambridge, MA (US);
Sean J. Harrison, Belmont, MA (US);
Shih-Chung Huang, Lexington, MA (US);
Liting Ma, Needham, MA (US);
MILLENNIUM PHARMACEUTICALS, INC., Cambridge, MA (US);
Abstract
Disclosed are chemical entities which are compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein R, R, and Rhave the values described herein. Chemical entities according to the disclosure can be useful as inhibitors of ATG7. Further provided are pharmaceutical compositions comprising a chemical entity of the disclosure and methods of using the compositions in the treatment of cancer.