The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Jun. 03, 2016
Applicants:

Uwm Research Foundation, Inc., Milwaukee, WI (US);

Medical University of Vienna, Vienna, AT;

Inventors:

James Cook, Milwaukee, WI (US);

Daniel Knutson, Elkhorn, WI (US);

Marko Mihovilovic, Perchtoldsdorf, AT;

Laurin Wimmer, Oberndorf, AT;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 471/14 (2006.01); A61K 31/4745 (2006.01); C07D 498/14 (2006.01); C07D 495/14 (2006.01); C07D 491/147 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 27/16 (2006.01); A61P 25/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4745 (2013.01); A61P 25/06 (2018.01); A61P 25/18 (2018.01); A61P 25/24 (2018.01); A61P 27/16 (2018.01); C07D 471/14 (2013.01); C07D 491/147 (2013.01); C07D 495/14 (2013.01); C07D 498/14 (2013.01);
Abstract

Provided herein are novel pyrazolo-quinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.


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