The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Sep. 27, 2018
Serina Therapeutics, Inc., Huntsville, AL (US);
J Milton Harris, Huntsville, AL (US);
Kunsang Yoon, Madison, AL (US);
Michael David Bentley, Huntsville, AL (US);
Zhihao Fang, Madison, AL (US);
Tacey Viegas, Madison, AL (US);
Francesco Maria Veronese, Padua, IT;
Anna Mero, Padua, IT;
Serina Therapeutics, Inc., Huntsville, AL (US);
Abstract
The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. In one embodiment, the POZ derivative is a terminally activated monofunctional POZ derivative.