The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Sep. 25, 2017
Applicant:
Medimmune Limited, Cambridge, GB;
Inventors:
Kris Sachsenmeier, Gaithersburg, MD (US);
Erin Sult, Gaithersburg, MD (US);
Carl Hay, Gaithersburg, MD (US);
Edmund Poon, Cambridge, GB;
Assignee:
MedImmune Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 31/519 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 31/519 (2013.01); C07K 16/2818 (2013.01); C07K 16/2896 (2013.01); C07K 16/40 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention provides therapeutic combinations featuring anti-CD73 antibodies (e.g., MEDI9447) and A2A receptor inhibitors and methods of using such combinations for reducing tumor-mediated immunosuppression.