The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Nov. 11, 2015
Applicant:
Trustees of Dartmouth College, Hanover, NH (US);
Inventor:
Dean R. Madden, Hanover, NH (US);
Assignee:
TRUSTEES OF DARTMOUTH COLLEGE, Hanover, NH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 31/4196 (2006.01); A61K 31/56 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); A61K 9/00 (2006.01); A61K 31/4439 (2006.01); A61K 31/473 (2006.01); A61K 31/4745 (2006.01); A61K 31/519 (2006.01); A61K 31/565 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 9/007 (2013.01); A61K 31/4196 (2013.01); A61K 31/4439 (2013.01); A61K 31/473 (2013.01); A61K 31/4745 (2013.01); A61K 31/519 (2013.01); A61K 31/56 (2013.01); A61K 31/565 (2013.01); A61K 45/06 (2013.01); C07K 7/08 (2013.01); C07K 14/4712 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01);
Abstract
Compositions and kits including an agent that inhibits the interaction between Disabled-2 and mutant CFTR proteins, optionally in combination with a CFTR corrector, CFTR potentiator, CAL inhibitor, mucolytic, anti-inflammatory agent or a combination thereof are provided as are methods for preventing or treating cystic fibrosis.