The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Nov. 04, 2015
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventor:

Rocky S. Tuan, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/57 (2015.01); A61L 27/22 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61K 47/32 (2006.01); A61K 47/42 (2017.01); A61K 9/06 (2006.01); A61L 27/16 (2006.01);
U.S. Cl.
CPC ...
A61K 35/57 (2013.01); A61K 9/06 (2013.01); A61K 47/32 (2013.01); A61K 47/42 (2013.01); A61L 27/16 (2013.01); A61L 27/222 (2013.01); A61L 27/3834 (2013.01); A61L 27/3847 (2013.01); A61L 27/3852 (2013.01); A61L 27/52 (2013.01); A61L 2300/64 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01);
Abstract

Methods are disclosed for forming bone and/or cartilage in an avian subject. The methods include administering to the avian subject a therapeutically effective amount of a composition comprising avian mesenchymal stem cells and a hydrogel that supports the differentiation of the avian mesenchymal stem cells into cells of an osteogenic and/or condrogenic lineage. In some embodiments, methods are disclosed for repairing a bone defect and preventing infection, such as that associated bone fracture, in an avian subject. The methods include administering locally to the bone defect a composition comprising a therapeutically effective amount of avian mesenchymal stem cells and a hydrogel, such as a methacrylated gelatin hydrogel.


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