The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Jan. 22, 2020
Applicants:

Nippon Suisan Kaisha, Ltd, Tokyo, JP;

Mochida Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Nobushige Doisaki, Hachioji, JP;

Shingo Arato, Hachioji, JP;

Takuro Fukae, Hachioji, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/23 (2006.01); A61K 31/20 (2006.01); A61K 31/232 (2006.01); C07C 67/03 (2006.01); C07C 67/54 (2006.01); C11C 3/10 (2006.01); C07C 69/587 (2006.01); C11B 3/12 (2006.01); C07C 67/56 (2006.01);
U.S. Cl.
CPC ...
A61K 31/232 (2013.01); C07C 67/03 (2013.01); C07C 67/54 (2013.01); C07C 67/56 (2013.01); C07C 69/587 (2013.01); C11B 3/12 (2013.01); C11C 3/10 (2013.01);
Abstract

Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.


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