The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Feb. 17, 2017
Applicants:

Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;

National Cancer Center, Gyeonggi-do, KR;

Inventors:

Jae Ho Cheong, Seoul, KR;

Soo Youl Kim, Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 47/59 (2017.01); A61P 35/04 (2006.01); A61K 31/4545 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 31/4545 (2013.01); A61K 47/10 (2013.01); A61K 47/59 (2017.08); A61P 35/04 (2018.01);
Abstract

The present invention relates to a pharmaceutical composition for treating cancer, containing a polyphenol compound as an active ingredient. The pharmaceutical composition according to the present study is very effective for the treatment and prognosis-improvement of cancer stem cells or cancer tissues having a magnitude of cancer stem cells such as poorly differentiated cancer. Further, the polyphenol compound and a biguanide compound, and an anticancer agent were observed to remarkably increase inhibitory effects on the growth of cancerous cells when they were administered to cancerous cells in combination rather than individually, thus the composition is expected to find great applications in the cancer therapy field.


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