The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Jun. 06, 2013
Applicant:

Adare Pharmaceuticals, Inc., Lawrenceville, NJ (US);

Inventors:

Gopi Venkatesh, Vandalia, OH (US);

Luigi Boltri, Agrate Brianza, IT;

Italo Colombo, Treviglio, IT;

Jin-Wang Lai, Springboro, OH (US);

Flavio Fabiani, Merate, IT;

Luigi Mapelli, Milan, IT;

Assignee:

Adare Pharmaceuticals, Inc., Lawrenceville, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 31/4406 (2006.01); A61K 31/4422 (2006.01); A61K 31/454 (2006.01); A61K 31/5513 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5026 (2013.01); A61K 9/5005 (2013.01); A61K 9/5042 (2013.01); A61K 9/5047 (2013.01); A61K 9/5078 (2013.01); A61K 9/5089 (2013.01); A61K 31/4406 (2013.01); A61K 31/4422 (2013.01); A61K 31/454 (2013.01); A61K 31/5513 (2013.01);
Abstract

The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 μg/mL at pH 6.8.


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