The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2020
Filed:
Jun. 08, 2017
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
New York University, New York, NY (US);
YongTae Kim, Suwanee, GA (US);
Zahi Fayad, Larchmont, NY (US);
Willem J. Mulder, New York, NY (US);
Edward Fisher, Scarsdale, NY (US);
Francois Fay, New York, NY (US);
Omid C. Farokhzad, Waban, MA (US);
Robert Langer, Newton, MA (US);
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
THE BRIGHAM AND WOMEN'S HOSPITAL, INC., Cambridge, MA (US);
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Abstract
Methods for making particles, such as nanoparticles, devices useful in the methods, and particles made by the method are described herein. The methods involves the use of microfluidic device, such that upon mixing solutions of the materials to form the particles (or a solution of the material or materials to form the particles and a non-solvent for the material or materials) at least two symmetrical microvortices are formed simultaneously. The method can be used to prepare polymeric or non-polymeric particles and hybrid particles, such as lipid-polymer hybrid particles, as well as such particles containing one or more agents associated with the particles.