The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

May. 09, 2017
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Jiang Du, San Diego, CA (US);

Yajun Ma, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); G01R 33/48 (2006.01); G01R 33/56 (2006.01); G16H 30/40 (2018.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/055 (2013.01); A61B 5/4504 (2013.01); A61B 5/4514 (2013.01); A61B 5/4523 (2013.01); A61B 5/4533 (2013.01); G01R 33/4816 (2013.01); G01R 33/4826 (2013.01); G01R 33/4828 (2013.01); G01R 33/5605 (2013.01); G16H 30/40 (2018.01); A61B 2576/00 (2013.01);
Abstract

Disclosed are methods and systems for ultrashort echo time magnetization transfer (UTE-MT) imaging and signal modeling to quantify the different proton groups, including free water, bound water and macromolecule protons in short T2 tissues such as the menisci, ligaments, tendons and cortical bone. UTE-MT images with a series of MT frequency offsets and MT power are subject to MT modeling to evaluate T1s, T2s, fractions and exchange rates of bound water, free water and macromolecule protons.


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