The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Mar. 12, 2019
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Vikas Gulani, Shaker Heights, OH (US);

Satyam Ghodasara, Cleveland, OH (US);

Katherine Wright, Macedonia, OH (US);

Nicole Seiberlich, Shaker Heights, OH (US);

Mark A. Griswold, Shaker Heights, OH (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/56 (2006.01); G01R 33/563 (2006.01); A61B 5/055 (2006.01); G01R 33/28 (2006.01); G01R 33/44 (2006.01);
U.S. Cl.
CPC ...
G01R 33/5602 (2013.01); A61B 5/055 (2013.01); G01R 33/5601 (2013.01); G01R 33/56308 (2013.01); G01R 33/281 (2013.01); G01R 33/443 (2013.01);
Abstract

A method for determining quantitative parameters for dynamic contrast-enhanced MR data includes acquiring a set of contrast-enhanced MR data for a region of interest using a T1-weighted pulse sequence, generating at least one contrast concentration curve based on the set of contrast-enhanced MR data, accessing a comprehensive dictionary of contrast concentration curves and generating a grouped dictionary that has a plurality of groups based on the comprehensive dictionary. Each group includes a plurality of correlated contrast concentration curves and a group representative signal for the group. The method also includes comparing a contrast concentration curve with the group representative signal of each group to select a group, comparing the contrast concentration curve to the plurality of correlated contrast concentration curves in the selected group to identify a set of quantitative parameters for the concentration curve and generating a report including the set of quantitative parameter.


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