The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Jun. 01, 2016
Applicant:

Medigene Immunotherapies Gmbh, Planegg-Martinsried, DE;

Inventors:

Dolores Schendel, Munich, DE;

Slavoljub Milosevic, Munich, DE;

Christian Ellinger, Munich, DE;

Carina Wehner, Munich, DE;

Assignee:

MEDIGENE IMMUNOTHERAPIES GMBH, Planegg-Martinsried, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C40B 40/10 (2006.01); C12N 15/10 (2006.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C40B 40/10 (2013.01); C12N 15/1093 (2013.01); C07K 14/7051 (2013.01); C12N 2740/10043 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/15043 (2013.01); C40B 40/08 (2013.01);
Abstract

The invention relates to a library for the expression of all functional TCR types comprising 45 TCR constructs each encoding one of the 45 different TCR α chains and 47 TCR constructs each encoding one of the 47 different TCR β chains, wherein each of the 45 TCR constructs encoding one of 45 different TCR α chain comprises the following building blocks one of the variable AV segments AVseg1 to AVseg45, and a constant AC segment, and wherein each of the 47 TCR constructs encoding one of 47 different TCR β chains comprises one of the variable BV segments BVseg1 to BVseg47, and a constant BC segment.


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