The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Nov. 19, 2015
Applicant:

Institute for Basic Science, Daejeon, KR;

Inventors:

Jin Soo Kim, Seoul, KR;

Tae Young Koo, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); C12N 15/864 (2006.01); C12N 15/867 (2006.01); C12N 9/16 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/746 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); C12N 15/867 (2013.01); C12N 15/8645 (2013.01);
Abstract

The present invention relates to a method for regulating gene expression, comprising introducing into a cell each of a recombinant vector which expresses a first domain comprising N-terminus of a Cas9 protein, and a recombinant vector which expresses a second domain comprising C-terminus of a Cas9 protein, a composition comprising the recombinant vectors, a kit for regulating gene expression, and a method for intracellular production of Cas9 protein. Moreover, the present invention relates to a transformed cell introduced with a viral vector which packages the first domain, and a viral vector which packages the second domain, and to a composition comprising a virus produced therefrom.


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