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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10858662 B1

PDFFull Text
Date of Patent:
Dec. 08, 2020

Filed:

Nov. 19, 2015

Genome editing with split cas9 expressed from two vectors

Applicant:

Institute for Basic Science, Daejeon, KR;

Inventors:

Jin Soo Kim, Seoul, KR;

Tae Young Koo, Seoul, KR;

Assignee:

INSTITUTE FOR BASIC SCIENCE, Daejeon, KR;

Attorney:

Lex IP Meister, PLLC

Primary Examiner:

Delia M Ramirez

Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); C12N 15/864 (2006.01); C12N 15/867 (2006.01); C12N 9/16 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/746 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); C12N 15/867 (2013.01); C12N 15/8645 (2013.01);
Abstract

The present invention relates to a method for regulating gene expression, comprising introducing into a cell each of a recombinant vector which expresses a first domain comprising N-terminus of a Cas9 protein, and a recombinant vector which expresses a second domain comprising C-terminus of a Cas9 protein, a composition comprising the recombinant vectors, a kit for regulating gene expression, and a method for intracellular production of Cas9 protein. Moreover, the present invention relates to a transformed cell introduced with a viral vector which packages the first domain, and a viral vector which packages the second domain, and to a composition comprising a virus produced therefrom.

Find Patent Forward Citations

Kim, Jin. (2020). Genome editing with split cas9 expressed from two vectors (U.S. Patent No. 10858662). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10858662

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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