The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Aug. 28, 2019
Applicant:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Inventors:
Yu-Chih Tsai, Fremont, CA (US);
Igor Vilfan, East Palo Alto, CA (US);
Khai Luong, San Francisco, CA (US);
Assignee:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01); C40B 50/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6869 (2013.01); C40B 50/06 (2013.01);
Abstract
Methods are provided for reducing the complexity of a population of nucleic acids prior to performing an analysis of the nucleic acids, e.g., sequence analysis. The methods result in a subset of the initial population enriched for a target region, which is typically located within one or more target fragments. The methods are particularly useful for analyzing populations having a high degree of complexity, e.g., chromosomal-derived DNA, whole genomic DNA, or mRNA populations.