The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Oct. 30, 2015
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Jeannie T. Lee, Cambridge, MA (US);
Kavitha Sarma, Waltham, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01); C12P 19/34 (2006.01); C40B 50/06 (2006.01); A61K 39/395 (2006.01); C40B 20/08 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); A61K 31/713 (2013.01); A61K 39/395 (2013.01); C12N 15/11 (2013.01); C12N 15/113 (2013.01); C12P 19/34 (2013.01); C40B 20/08 (2013.01); C40B 50/06 (2013.01); C12N 5/00 (2013.01); C12N 2310/113 (2013.01); C12N 2310/1241 (2013.01); C12N 2310/14 (2013.01); C12N 2310/15 (2013.01); C12N 2310/531 (2013.01); C12N 2320/11 (2013.01); C12N 2330/31 (2013.01); G01N 2333/914 (2013.01); G01N 2500/02 (2013.01);
Abstract
Methods and compositions for modulation of the activity of alpha thalassemia/mental retardation syndrome X-linked (ATRX), e.g., modulation of DNA-ATRX or RNA-ATRX interactions, and methods for identifying and using compounds that modulate DNA-ATRX or RNA-ATRX interactions, as well as the compounds themselves.