The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Nov. 24, 2016
Applicants:

Junshi Biosciences Co., Ltd., Shanghai, CN;

Jungmeng Biosciences Co., Ltd., Suzhou, Jiangsu, CN;

Inventors:

Hai Wu, Shanghai, CN;

Bo Chen, Shanghai, CN;

Hui Feng, Shanghai, CN;

Sheng Yao, Shanghai, CN;

Jian Yao, Shanghai, CN;

Hongchuan Liu, Shanghai, CN;

Libo Zhang, Shanghai, CN;

Jing Zhang, Shanghai, CN;

Dan Meng, Shanghai, CN;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61P 3/06 (2006.01); A61K 51/00 (2006.01); A61K 51/10 (2006.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/395 (2013.01); A61K 47/6871 (2017.08); A61K 51/00 (2013.01); A61K 51/1075 (2013.01); A61P 3/06 (2018.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention provides an antibody or a functional fragment thereof that specifically binds to Proprotein convertase subtilisin/kexin type 9 (PCSK9) with high affinity, also provides a nucleic acid molecule encoding the antibody of the invention or the functional fragment thereof, for expressing an expression vector and a host cell of the antibody or the functional fragment thereof, and also provides a method for producing the antibody or the functional fragment thereof. The present invention provides that the antibody or the functional fragment thereof is used for treating diseases such as dyslipidemia.


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