logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10858436 B1

PDFFull Text
Date of Patent:
Dec. 08, 2020

Filed:

Jul. 08, 2015

Psgl-1 modulators and uses thereof

Applicant:

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);

Inventors:

Linda M. Bradley, La Jolla, CA (US);

Roberto Tinoco, La Jolla, CA (US);

Assignee:

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, La Jolla, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Rodney P Swartz

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/002 (2006.01); A61K 45/00 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2854 (2013.01); C07K 14/70596 (2013.01); C07K 16/2896 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention relates to the seminal discovery that P-selectin glycoprotein ligand-1 (PSGL-1) modulates the immune system and immune responses. Specifically, the present invention provides PSGL-1 agonists and antagonists which increase the survival of multifunctional T cells and viral clearance. The present invention further provides methods of treating infectious diseases, cancer and immune and inflammatory diseases and disorders using a PSGL-1 modulator.

Find Patent Forward Citations

Bradley, Linda. (2020). Psgl-1 modulators and uses thereof (U.S. Patent No. 10858436). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10858436

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…