The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Aug. 25, 2017
Applicant:

Cem Corporation, Matthews, NC (US);

Inventors:

Jonathan M. Collins, Charlotte, NC (US);

Sandeep K. Singh, Matthews, NC (US);

Assignee:

CEM Corporation, Matthews, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/08 (2006.01); C07K 1/10 (2006.01); C07K 1/107 (2006.01); C07K 1/04 (2006.01); C07C 267/00 (2006.01); C07K 1/06 (2006.01);
U.S. Cl.
CPC ...
C07K 1/1075 (2013.01); C07C 267/00 (2013.01); C07K 1/04 (2013.01); C07K 1/045 (2013.01); C07K 1/061 (2013.01); C07K 1/082 (2013.01); C07K 1/084 (2013.01); C07K 1/10 (2013.01);
Abstract

An improved method of coupling amino acids into peptides or peptidomimetics is disclosed in which the activation and coupling are carried out in the same vessel, in the presence of a carbodiimide in an amount greater than 1 equivalent as compared to the amino acid, in the presence of an activator additive, and at a temperature greater than 30° C.


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