The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Feb. 12, 2019
Cyclerion Therapeutics, Inc., Cambridge, MA (US);
Glen Robert Rennie, Somerville, MA (US);
Rajesh R. Iyengar, West Newton, MA (US);
Thomas Wai-Ho Lee, Lexington, MA (US);
Takashi Nakai, Newton, MA (US);
Ara Mermerian, Waltham, MA (US);
Lei Jia, San Diego, CA (US);
G-Yoon Jamie Im, Cambridge, MA (US);
Paul Allan Renhowe, Sudbury, MA (US);
Joon Jung, Newton, MA (US);
Peter Germano, Newton, MA (US);
Karthik Iyer, Cambridge, MA (US);
Timothy Claude Barden, Waltham, MA (US);
Kim Tang, Belmont, MA (US);
Cyclerion Therapeutics, Inc., Cambridge, MA (US);
Abstract
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. The compounds are of Formula I: