The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Jul. 07, 2017
Applicants:

Merck Sharp & Dohme Corp., North Wales, PA (US);

Lawrence Livermore National Security, Llc, Livermore, CA (US);

Inventors:

Daniel Bensen, Carlsbad, CA (US);

Zhiyong Chen, San Diego, CA (US);

John Finn, Encinitas, CA (US);

Thanh T. Lam, San Diego, CA (US);

Suk J. Lee, San Diego, CA (US);

Xiaoming Li, San Diego, CA (US);

Douglas W. Phillipson, Del Mar, CA (US);

Leslie W. Tari, San Diego, CA (US);

Michael Trzoss, San Diego, CA (US);

Junhu Zhang, San Diego, CA (US);

Felice C. Lightstone, Fremont, CA (US);

Toan B. Nguyen, Marlborough, CA (US);

Sergio E. Wong, Tracy, CA (US);

Paul Aristoff, Dexter, MI (US);

Michael Jung, Los Angeles, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 487/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 487/14 (2013.01);
Abstract

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.


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