The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Jun. 07, 2017
Applicant:
Jacobio Pharmaceuticals Co., Ltd., Beijing, CN;
Inventors:
Cunbo Ma, Beijing, CN;
Panliang Gao, Beijing, CN;
Jie Chu, Beijing, CN;
Xinping Wu, Beijing, CN;
Chunwei Wen, Beijing, CN;
Di Kang, Beijing, CN;
Jinlong Bai, Beijing, CN;
Xiaoyan Pei, Beijing, CN;
Assignee:
JACOBIO PHARMACEUTICALS CO., LTD., Beijing, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 471/14 (2006.01); C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 491/107 (2006.01); A61P 35/00 (2006.01); C07D 413/14 (2006.01); C07D 471/20 (2006.01); C07D 405/14 (2006.01); A61P 37/00 (2006.01); A61P 27/00 (2006.01); A61P 9/00 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61P 9/00 (2018.01); A61P 27/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 471/20 (2013.01); C07D 491/107 (2013.01); C07D 519/00 (2013.01);
Abstract
Provided are certain novel pyrazine derivatives (I) as SHP2 inhibitors which is shown as formula (I), their synthesis and their use for treating a SHP2 mediated disorder. More particularly, provided are fused heterocyclic derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder.